polarographic determination of certain cephalosporins in pharmaceutical preparations

Kinetic Spectrophotometric Determination of Certain Cephalosporins in Pharmaceutical Formulations

A simple, reliable, and sensitive kinetic spectrophotometric method was developed for determination of eight cephalosporin antibiotics, namely, Cefotaxime sodium, Cephapirin sodium, Cephradine dihydrate, Cephalexin monohydrate, Ceftazidime pentahydrate, Cefazoline sodium, Ceftriaxone sodium, and Cefuroxime sodium. The method depends on oxidation of each of studied drugs with alkaline potassium ...

Spectrophotometric Determination of Certain Macrolide Antibiotics in Pharmaceutical Preparations

A direct colorimetric method was described for the rapid, sensitive and accurate determination of certain macrolide antibiotics; roxithromycin (ROX), azithromycin (AZM), and clarithromycin (CLM) in bulk powder and in pharmaceutical preparations. The proposed method is based on reaction of the studied drugs with haematoxylin reagent in the presence of boric acid to give a reddish-violet chromoge...

Spectrophotometric determination of certain vicinal dihydroxybenzene derivatives in pharmaceutical preparations.

A simple, rapid and sensitive spectrophotometric method for the assay of certain adrenergic drugs, [pyrocatechol (PC), levodopa (LD), methyldopa (MD) and dopamine (DP)] is described. The method involves the oxidation of o-dihydroxybenzene derivatives by K2CrO4 followed by oxidative coupling with sulfanilic acid (SPA), leading to the formation of a red or violet colored product having maximum ab...

A Direct Current Polarographic Method for the Determination of Chlorpheniramine Maleate in Pharmaceutical Preparations

A direct polarographic method for the determination of chlorpheniramine maleate in pharmaceutical preparations had been developed. The method was based on the reduction of chlorpheniramine maleate in an acidic medium (pH 1.2-4.0). The effect of pH on the polarographic wave was investigated by recording d.c. polarograms in various supporting electrolytes. The calibration graphs were rectilinear ...

Spectrophotometric Determination of Cephalosporins in Pharmaceutical Samples

Spectrophotometric determination of certain cephalosporins in pure form and in pharmaceutical formulations.

A simple and reproducible spectrophotometeric method for the assay of cefotaxime sodium, cefuroxime sodium, and ceftriaxone disodium with metol-chromium(VI) reagent has been developed. The procedure is based on direct oxidation of metol by potassium dichromate in presence of drug in acidic medium and subsequent formation of ternary complex. Beer's law is obeyed in the range 0.2-28 microg ml(-1)...